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Zhangxinjie

Associate professor

Department: College of Mechanical and Electrical Engineering

Subject:

Teach Department:

Tel:

Email: xj.zhang@hhu.edu.cn

Office: Yingcai Building 215

Address: North Jinling Road No.200, Changzhou

PostCode: 213022

10 Access

Resume

We study the physics of fluidic control in microvalves, the inertial focusing and separation of biological cells and microdroplets generation in confined microchannels. We develop microfluidic-based equipment for automated cancer cell separation.

We also develop soft valves and pneumatic  actuators for robotic control, e.g.,  soft grippers to grasp complex objects.

About

  • Name: Zhangxinjie
  • Gender: male
  • Degree: Ph. D
  • Date of Birth: 1984-03-17 00:00:00.0
  • Education Level:
  • Alma Mater: Southeast University

Education Experiences

Southeast University (Dec. 2018 – Present) Postdoctoral Fellow in School of Mechanical Engineering

Southeast University (Mar. 2013 – Sept. 2017) PhD in School of Mechanical Engineering

Southeast University (Sept. 2006 – Apr. 2009) ME in School of Mechanical Engineering

Hefei University of Technology (Sept. 2002 – Jun. 2006) BA in School of Mechanical Engineering


WorkExperience

Hohai University (May 2021  Present) Associate Professor 

Hohai University (Nov. 2017 – May 2021) Lecturer

Changzhou HOHE New Energy Science and Technology Co., Ltd. (Jul. 2012 – Mar. 2013) R&D Manager

United Automotive Electronic Systems Co., Ltd. (Jul. 2010 – Jun. 2012) Mechanical Engineer

Changlin Co., Ltd. (Jul. 2009 – Jun. 2010) Mechanical Engineer

Field

Inertial microfluidics for cell manipulation

Microfluidic valves/pumps for precise flow control

Microfluidic droplets for single cell analysis

Soft robots and components


Project

Changzhou Sci and Tech Program, CE20225046, “Research on tumor cell isolation and clinic application based on microfluidic technology”, Apr. 2022 – Apr. 2024.

Fundamental Research Funds for the Central Universities, B220202024, “Research on the oscillating effect of self-activated microfluidic valve”, Jan. 2022 – Dec. 2023.

National Natural Science Foundation of China, 50905150, “Research on the Mechanism of Biological Cell Inertial Separation Precisely Controlled by Asymmetry Second Flow in Special-shaped Cross-sections”, Jan. 2020 – Dec. 2022.

Natural Science Foundation of Jiangsu Province, BK20190167, “Research on the Key Technology of Microfluidic Flow Regulator for High Flow Regulation under Low-Threshold Pressures”, Jul. 2019 – Jun. 2022.

Industry Project, “Development of Bearing Flexible Assembling System”, Nov. 2020 – Oct. 2022.

China Postdoctoral Science Foundation, 2020T130097, “Flexible Bionic Actuators for Soft Robots”, Jan. 2020 – Dec. 2021.

Fundamental Research Funds for the Central Universities, B200202230, “A Manufacturing Strategy for Microfluidic Chips of Complex Structures”, Jan. 2020 – Dec. 2021.

Leading Talents Entrepreneurship Project of Changzhou City, “Development of Transmission Shifting System for Commercial Vehicles”, 2020.

Changzhou Sci and Tech Program, CJ20190054, “Inertial Microfluidic Chip for Biological Cell Manipulation”, May 2019 – Apr. 2021.

China Postdoctoral Science Foundation, 2019M651643, “Mechanism of Microfluidic Passive Valve for Autonomous Flow Regulation”, Jan. 2019 – Dec. 2020.

Jiangsu Planned Projects for Postdoctoral Research Funds, 2019K033, “Inertial Migration of Biological Cells Controlled by Asymmetry Second Flow in Spiral Channels”, Jan. 2019 – Dec. 2020.

Fundamental Research Funds for the Central Universities, 2018B04014, “Investigation of Passive Flow Regulators for Stable Flow Control”, Jan. 2018 – Dec. 2019.

Open Research Fund from Southeast University, KF201801, “Research on the Flow Regulation Mechanism of Microfluidic Passive valve”, Jan. 2018 – Dec. 2019.

Thesis

1.Xinjie Zhang*, Ayobami Elisha Oseyemi, Ke Ma, Shouyi Yu. Entirely soft valve leveraging snap-through instability for passive flow control. Sensors and Actuators B: Chemical2022, 367, 132035.

2.Shuai Han, Xinjie Zhang*, Qiao Gu, Yao Liu, Xinyi Wang. Inertial focusing effect of particles in spiral microchannel with asymmetric cross-section. Optics and Precision Engineering2022, 30(3): 310-319. (In Chinese)

3.Xinjie Zhang*, Ayobami Elisha Oseyemi. A herringbone soft pneu-net actuator for enhanced conformal gripping. Robotica2022, 40: 1345-1360.

4.Xinjie Zhang*, Ayobami Elisha Oseyemi, Shouyi Yu and Qiao Gu. Fully soft valve for autonomous pressure control. 2021 3rd International Symposium on Robotics & Intelligent Manufacturing Technology (ISRIMT), Sept 24-26, 2021, Changzhou, China, pp. 118-121 (Best Paper Award)

5.Ayobami Elisha Oseyemi, Xinjie Zhang*. Theoretical modeling of the behavior of a parallel membrane passive flow regulator. Sensors and Actuators A: Physical2020, 315, 112310.

6.Xinjie Zhang*, Kang Xia, Aimin Ji. A portable plug-and-play syringe pump using passive valves for microfluidic applications, Sensors and Actuators B: Chemical2020, 304, 127331.

7.Xinjie Zhang*, Jieming Chen. Design and characterization of passive microvalve for high-throughput flow control under low threshold pressure, Instrument Technique and Sensor2020, 5: 24–27. (In Chinese)

8.Xinjie Zhang*, Ayobami Elisha Oseyemi. Microfluidic passive valve with ultra-low threshold pressure for high-throughput liquid delivery, Micromachines2019, 10(12), 798.

9.Xinjie Zhang*, Zhenyu Zhang. Microfluidic passive flow regulatory device with an integrated check valve for enhanced flow control, Micromachines2019, 10(10), 653.

10.Xinjie Zhang*, kang Xia, Aimin Ji, Nan Xiang*. A smart and portable micropump for stable liquid delivery, Electrophoresis201940(6): 865–872.

11.Xinjie Zhang, Zhixian Zhu, Feifei Long, Nan Xiang*, Ni Zhonghua*. Automated microfluidic instrument for label-free and high-throughput cell separation, Analytical Chemistry2018, 90(6): 4212–4220.

12.Xinjie Zhang, Zhixian Zhu, Zhonghua Ni, Nan Xiang*, Hong Yi*. Inexpensive, rapid fabrication of polymer-film microfluidic autoregulatory valves for disposable microfluidics. Biomedical Microdevices2017, 19(2): 21.

13.Xinjie Zhang, Zhixian Zhu, Nan Xiang*, Zhonghua Ni*. A microfluidic gas dampener for stabilizing gas pressure in disposable microfluidic systems, Biomicrofluidics2016, 10(5), 054123.

14.Xinjie Zhang, Xin Wang, Ke Chen, Jie Cheng, Nan Xiang*, Zhonghua Ni*. Passive flow regulator for precise high-throughput flow rate control in microfluidic environments, RSC Advances2016, 6(38): 31639–31646.

15.Xinjie Zhang, Di Huang, Wenlai Tang, Di Jiang, Ke Chen, Hong Yi, Nan Xiang*, Zhonghua Ni*. A low cost and quasi-commercial polymer film chip for high-throughput inertial cell isolation. RSC Advances2016, 6(12): 9734–9742.

16.Nan Xiang*, Xinjie Zhang, Qing Dai, Jie Cheng, Ke Chen, Zhonghua Ni*. Fundamentals of elasto-inertial particle focusing in curved microfluidic channels. Lab on a Chip2016, 16(14): 2626–2635.

17.Nan Xiang, Di Huang, Jie Cheng, Ke Chen, Xinjie Zhang, Wenlai Tang, Zhonghua Ni*. Focusing dynamics of finite-sized particles in confined microfluidic channels. Applied Physics Express2016, 9(2), 027001.

18.Xinjie Zhang, Nan Xiang, Wenlai Tang, Di Huang, Xin Wang, Hong Yi, Zhonghua Ni*. A passive flow regulator with low threshold pressure for high-throughput inertial isolation of microbeads, Lab on a Chip2015, 15(17): 3473–3480. (Inside Front cover)

19.Nan Xiang, Zhiguo Shi, Wenlai Tang, Di Huang, Xinjie Zhang, Zhonghua Ni*. Improved understanding of particle migration modes in spiral inertial microfluidic devices. RSC Advances2015, 5(94): 77264–77273.

20.Wenlai Tang, Nan Xiang, Xinjie Zhang, Di Huang, Zhonghua Ni*. Dynamic process and flow-rate regulation mechanism of particle inertial focusing in an asymmetric ally curved microchannel. Acta Physica Sinica2015, 64(18): 387–397.

21.Di Huang, Nan Xiang, Wenlai Tang, Xinjie Zhang, Zhonghua Ni*. Microfluidics-based circulating tumor cells separation. Progress in Chemistry2015, 27(7): 882–912.

22.Wenlai Tang, Nan Xiang, Di Huang, Xinjie Zhang, Xingzhong Gu, Zhonghua Ni*. Microfluidics-based single-cell biophysical characterization. Progress in Chemistry2014, 26(6): 1050–1064.

23.Zhonghua Ni*, Xinjie Zhang. Molecular dynamics simulation for aggregation phenomena of nanocolloids. Science in China-Series E: Technological Sciences2009, 52(2): 484–490.

24.Zhonghua Ni*, Xinjie Zhang, Hong Yi. Separation of nanocolloids driven by dielectrophoresis: a molecular dynamics simulation. Science in China-Series E: Technological Sciences2009, 52(7): 1874–1881.

25.Xinjie Zhang, Zhonghua Ni*. Molecular dynamics simulation for dielectrophoresis of nanoparticles. Journal of Southeast University (Natural Science Edition)2008, 38(5): 884–888. (in Chinese)

26.Xinjie Zhang, Zhonghua Ni*. Molecular dynamics simulation of nanocolloid movement driven by dielectrophoresis. Academic Conference on the Anniversary of Postgraduates of Southeast University2008, No: 080704. (in Chinese)



Achievements

Xinjie Zhang, Kang Xia, Aimin Ji. A soft valve for quickly switching flow path. Chinese patent number ZL 2020 10119076.1. (in Chinese)

Xinjie Zhang, Kang Xia, Aimin Ji. A soft actuator. Chinese patent number ZL 2020 1 0119036.7. (in Chinese)

Xinjie Zhang. An inertial microfluidic device for manipulating micro/nano-particles. Chinese patent number ZL 2019 1 0334273.2. (in Chinese)

Xinjie Zhang, Aimin Ji, Lin Zhang, Kang Xia. A portable precise micropump. Chinese patent number ZL 2019 1 0674929.5. (in Chinese)

Xinjie Zhang. A microvalve for flow regulation. Chinese patent number ZL 2018 1 1171570.1. (in Chinese)

Xinjie Zhang. A precise pneumatic-driven micropump. Chinese patent number ZL 2018 1 1167111.6. (in Chinese)

Xinjie Zhang. Microfluidic passive valve with a ring membrane for flow regulation. Chinese patent number ZL 2018 1 0502408.7. (in Chinese)

Zhonghua Ni, Xinjie Zhang, Nan Xiang. A microfluidic gas damper and its flow resistance regulation method. Chinese patent number ZL 2016 1 0346327.3. (in Chinese)

Zhonghua Ni, Xinjie Zhang. A sandwich microfluidic device and its manufacturing method. Chinese patent number ZL 2015 1 0766988.7. (in Chinese)

Xinjie Zhang. A self-decarbonization heat exchanger. Chinese patent number ZL 2012 1 0129465.8. (in Chinese)

Open Course

Undergraduate Course (in Chinese)

Interchangeability and Measurement Technology, Hohai University, 2019 – Present

Production Practice, Hohai University, 2019 – Present

Fundamentals of Mechanical Design, Hohai University, 2019 – PresentI

Introduction to Mechanical Engineering, Hohai University, 2019


International Postgraduate Course (in English)

Modern Testing and Measurement Technology, Hohai University, 2019 – Present

Teaching achievements

Teaching resources

Social Position

Senior Member of Chinese Mechanical Engineering Society (Dec. 2021 – Present)

Co-founder of Changzhou Huasheng Transmission Co., Ltd. (Sept. 2020 – Present)

Senior Member of Chinese Society of Micro-Nano Technology (Nov. 2019 – Present)

Member of Changzhou Science and Technology League of Youth (Sept. 2019  Present)

Technical Advisor of Changzhou Dongfeng Bearing Co., Ltd. (Dec. 2018  Present)

Honor

The 16th Excellent Scientific Paper Award of Natural Science, Second Prize, Changzhou City, 2021

Nominated Twice for Excellent Advisor of Bachelor’s Degree Thesis, Hohai University, 2020 and 2021

Teaching Achievement Award, First Prize, Hohai University, 2020

The 27th Teaching Contest Award, First Prize, Hohai University, 2020

Nominated as Excellent Individual, Jiusan Society, 2020

Nominated Twice for Excellent Individual in Annual Assessment, Hohai University, 2019 and 2020

Excellent Doctor Degree Dissertation Award, Southeast University, 2019

Nominated as High-level Innovation and Entrepreneurship Talent, Jiangsu Province, 2018

National Scholarship for Doctoral Students, China, 2016

“One Point Lesson” Award, United Automotive Electronic Systems Co., Ltd., 2011

Excellent Master Degree Dissertation Award, Jiangsu Province, 2010

Excellent Postgraduate Scholarship, Southeast University, 2007 and 2008


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